Differential diagnosis of neonatal cholestasis: clinical and laboratory parameters

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Differential diagnosis of neonatal cholestasis: clinical and laboratory parameters.

OBJECTIVE To evaluate if clinical and laboratory parameters could assist in the differential diagnosis of intra and extra-hepatic neonatal cholestasis (NC). METHODS Retrospective study of NC patients admitted at the Pediatric Hepatology Outpatient Clinic of the teaching hospital of Universidade Estadual de Campinas (UNICAMP), Campinas, Brazil, between December 1980 and March 2005. The approac...

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Diagnosis of Neonatal Cholestasis

Cholestasis is frequent in neonates (1/2,500 live births) and in young children. It includes many etiologies with sometimes poor prognosis. In case of neonatal cholestasis, the most important point is to look at the stool color and to rule out biliary atresia which needs to be surgically treated before the 45th day of life. Biliary atresia represents almost 50% of cases of neonatal cholestasis,...

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The purpose of this study was to describe and compare the clinical, laboratory and health care characteristics of newborns (NBs) with confirmed late onset sepsis and NBs with unconfirmed late sepsis, verify if there were any differences between the groups, and describe the germs prevalent in the studied neonatal unit. This is a descriptive study, involving 168 cases. It was observer that 33.3% ...

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Evaluation of Neonatal Hemolytic Jaundice: Clinical and Laboratory Parameters

BACKGROUND Neonatal jaundice that occurs in ABO or Rhesus issoimunisation has been recognized as one of the major risk factors for development of severe hyperbilirubinemia and bilirubin neurotoxicity. AIM Aim of our study was to investigate clinical and laboratory parameters associated with hemolytic jaundice due to Rh and ABO incompatibility and compare results with the group of unspecific j...

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Diagnosis of neonatal sepsis: a clinical and laboratory challenge.

The evaluation of tests for neonatal sepsis is important because the infection may present a very serious threat to the baby. There is an urgent need to know whether the baby has sepsis to institute treatment as quickly as possible. Confirmation of the diagnosis may take time, and diagnostic tests are used to obtain a rapid indication of the infection status. These tests are not perfect. Some r...

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ژورنال

عنوان ژورنال: Jornal de Pediatria

سال: 2010

ISSN: 0021-7557

DOI: 10.2223/jped.1970